BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A

PHASE2TerminatedINTERVENTIONAL
Enrollment

143

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

April 30, 2010

Study Completion Date

October 31, 2010

Conditions
Hemophilia A
Interventions
BIOLOGICAL

rFVIII-FS/pegylated liposomes (BAY79-4980)

35 IU/kg body weight intravenous 1x/week for 52 weeks This arm will be stopped by 30.04.10 the subjects will be offered to change to the active comparator arm

BIOLOGICAL

rFVIII-FS/WFI (BAY14-2222)

25 IU/kg body weight intravenous 3x/week for 52 weeks

Trial Locations (95)

500

Changhua

1020

Bruxelles - Brussel

1023

Auckland

1090

Vienna

1200

Bruxelles - Brussel

2132

Johannesburg

3000

Leuven

3010

Bern

6000

Perth

8001

Christchurch

8036

Graz

8200

Århus N

10000

Zagreb

10002

Taipei

10126

Torino

10249

Berlin

11217

Taipei

13005

Marseille

13419

Tallinn

14215

Buffalo

14621

Rochester

15213

Pittsburgh

20122

Milan

25030

Besançon

28046

Madrid

33006

Oviedo

34059

Montpellier

35033

Rennes

38009

Santa Cruz de Tenerife

41013

Seville

45229

Cincinnati

46026

Valencia

48143

Münster

48202

Detroit

48823

East Lansing

50035

Brasov

50134

Florence

50809

Klaipėda

52621

Tel Litwinsky

53105

Bonn

53226

Milwaukee

55905

Rochester

67091

Strasbourg

69437

Lyon

75015

Paris

75674

Paris

77030

Houston

80045

Aurora

80131

Napoli

80144

Napoli

92868

Orange

94275

Le Kremlin-Bicêtre

95124

Catania

95817

Sacramento

300011

Timișoara

94143-0324

San Francisco

70112-2699

New Orleans

02115

Boston

64108-9898

Kansas City

89109-2803

Las Vegas

87131-0001

Albuquerque

27157-1009

Winston-Salem

19104-0506

Philadelphia

C1221ADC

Buenos Aires

C1425AUM

Buenos Aires

S2000CKF

Rosario

T2N 2T9

Calgary

T6G 2C8

Edmonton

B3H 2Y9

Halifax

L8S 4J9

Hamilton

K1H 8L6

Ottawa

M5B 1W8

Toronto

M5G 1X8

Toronto

Unknown

Santiago

08661

Vilnius

9713 GZ

Groningen

6525 GA

Nijmegen

3508 GA

Utrecht

0027

Oslo

80-952

Gdansk

31-501

Krakow

93-510

Lodz

61-833

Poznan

02-776

Warsaw

022328

Bucharest

08035

Barcelona

01-330

Adana

07059

Antalya

35-100

Izmir

CB2 0QQ

Cambridge

SE1 7EH

London

M13 9WL

Manchester

CF14 4XW

Cardiff

S10 2JF

Sheffield

B15 2TH

Birmingham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY