275
Participants
Start Date
December 31, 2002
Primary Completion Date
July 31, 2013
Study Completion Date
July 31, 2013
pneumococcal conjugate vaccine
"Prevnar is manufactured as a liquid preparation. Each 0.5 mL dose is formulated to contain:~2 μg of each saccharide for serotypes 4, 9V, 14, 18C, 19F, and 23F, and 4 μg of serotype 6B per dose (16 μg total saccharide); approximately 20 μg of CRM197 carrier protein; and 0.125 mg of aluminum per 0.5 mL dose as aluminum phosphate adjuvant. After shaking, the vaccine is a homogeneous, white suspension."
pneumococcal polysaccharide vaccine
PNEUMOVAX 23 is manufactured according to methods developed by the Merck Research Laboratories. Each 0.5 mL dose of vaccine contains 25 μg of each polysaccharide type in isotonic saline solution containing 0.25% phenol as a preservative.
Walter Reed Army Medical Center, Washington D.C.
National Naval Medical Center, Bethesda
Naval Medical Center Portsmouth, Portsmouth
San Antonio Military Medical Center, Lackland Air Force Base
Naval Medical Center San Diego, San Diego
Tripler Army Medical Center, Tripler AMC
Infectious Diseases Clinical Research Program
OTHER
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
US Military HIV Research Program
NETWORK
Uniformed Services University of the Health Sciences
FED
Henry M. Jackson Foundation for the Advancement of Military Medicine
OTHER