Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients of Different Ages With Metastatic Breast Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 11, 2008

Primary Completion Date

October 25, 2011

Study Completion Date

April 24, 2026

Conditions
Breast Cancer
Interventions
DRUG

paclitaxel albumin-stabilized nanoparticle formulation

100 mg/m2 3 weeks on 1 week off

OTHER

pharmacological study

Cycle 1, week 1 at 0, 0.25, 0.5, 1, 1.5, 2, 4, 6, 8, 24 and 48 hours

OTHER

physiologic testing

Prior to treatment, at the end of 2 cycles of therapy and upon completion of therapy

OTHER

questionnaire administration

Prior to treatment, at the end of 2 cycles of therapy and upon completion of therapy

OTHER

study of socioeconomic and demographic variables

Prior to treatment, at the end of 2 cycles of therapy and upon completion of therapy

PROCEDURE

cognitive assessment

Prior to treatment, at the end of 2 cycles of therapy and upon completion of therapy

PROCEDURE

psychosocial assessment and care

Prior to treatment, at the end of 2 cycles of therapy and upon completion of therapy

Trial Locations (2)

91105

City of Hope Medical Group, Pasadena

91010-3000

City of Hope Medical Center, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER