13
Participants
Start Date
December 31, 2007
Primary Completion Date
December 31, 2008
Study Completion Date
December 31, 2008
Valproic Acid
The investigators will utilize intravenous sodium valproate at visit 3. Dosage will be individualized to each patient's body weight, age, and hepatic-enzyme-inducing status. Intravenous VPA dose predictions will be based upon population VPA pharmacokinetic parameters (Dutta 2003).
Placebo
Each patient will have a placebo-infusion (with 0.9% NS or D5W) of 12-hour duration at visit 2.
Vanderbilt University, Nashville
The Comprehensive Epilepsy Care Center for Children & Adults, Chesterfield
Collaborators (1)
Abbott
INDUSTRY
Vanderbilt University Medical Center
OTHER