A Phase 1/2 Study of CS7017, an Oral PPARγ Agonist, in Combination With Paclitaxel

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

January 31, 2008

Primary Completion Date

December 31, 2011

Study Completion Date

December 31, 2011

Conditions
Anaplastic Thyroid Cancer
Interventions
DRUG

CS-7017

At Phase 1, CS-7017 will be tested in combination with paclitaxel at the following dosage levels: 0.15, 0.30, or 0.50 mg BID. At Phase 2, CS-7017 will be administered at the recommended phase 2 dose (RP2D).

DRUG

Paclitaxel

Commercially available paclitaxel will be administrated as IV infusion over 3 hours once every 3 weeks.

Trial Locations (10)

19104

University of Pennsylvania Maloney Hospital, Philadelphia

23507

Eastern Virginia Medical School, Norfolk

32224

Mayo Clinic, Jacksonville

37232

Vanderbilt Ingram Cancer Center, Nashville

43210

Ohio State Univ, Columbus

55905

Mayo Clinic, Rochester

63110

Washington University, Siteman Cancer Center, St Louis

80045

Univ of Colorado Cancer Center, Aurora

97239

Oregon Health Science Univ, Portland

02115

Massachusetts General Hospital, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Daiichi Sankyo

INDUSTRY

NCT00603941 - A Phase 1/2 Study of CS7017, an Oral PPARγ Agonist, in Combination With Paclitaxel | Biotech Hunter | Biotech Hunter