84
Participants
Start Date
May 31, 2008
Primary Completion Date
May 31, 2013
Study Completion Date
January 31, 2016
Carfilzomib
Carfilzomib for Injection was administered intravenously over 10 minutes on Days 1, 2, 8, 9, 15, and 16 of a 28-day cycle for the first 12 cycles. Each dose of Carfilzomib for Injection was normalized to body surface area.
Lenalidomide
Lenalidomide was administered orally on Days 1 to 21 of each 28-day cycle.
Dexamethasone
Dexamethasone 40 mg orally or intravenous equivalent was administered 30 minutes to 4 hours before carfilzomib on Days 1, 8, and 15, as well as on Day 22 of each 28-day cycle.
Cornell University, New York
H. Lee Moffitt Cancer Center & Research Institute, Tampa
Gabrail Cancer Center, Canton
Medical College of Wisconsin, Milwaukee
Northwestern University, Chicago
MD Anderson Cancer Center, Houston
Cedars Sinai Medical Center, Los Angeles
Pacific Shores Medical Group, Long Beach
University of California San Francisco, San Francisco
Hackensack University Medical Center, Hackensack
Fred Hutch Cancer Research Center, Seattle
Jewish General Hospital, Montreal
Lead Sponsor
Amgen
INDUSTRY