112
Participants
Start Date
January 14, 2008
Primary Completion Date
April 28, 2020
Study Completion Date
October 28, 2022
Nifurtimox
30mg/kg/day PO divided into TID dosing q day
Cyclophosphamide
250 mg/m2/dose in normal saline, IV, infused over 30 minutes on days 1-5 of each cycle.
Topotecan
0.75mg/m2/dose, in normal saline, IV, infused over 30 minutes on days 1-5 of each cycle.
Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey
Levine Children's Hospital, Charlotte
Medical University of South Carolina, Charleston
Arnold Palmer Hospital for Children- MD Anderson, Orlando
Helen DeVos Children's Hospital, Grand Rapids
Children's Hospital and Clinics on Minnesota, Minneapolis
Cardinal Glennon Children's Medical Center, St Louis
Children's Mercy Hospitals and Clinics, Kansas City
Children's Medical Center, Dallas
Texas Children's Cancer and Hematology Centers, Houston
Primary Children's Hospital, Salt Lake City
Rady Children's Hospital, San Diego
Kapiolani Medical Center for Women and Children, Honolulu
Connecticut Children's Hospital, Hartford
Tufts Medical Center, Boston
Collaborators (1)
Bayer
INDUSTRY
Giselle Sholler
OTHER