Alternative Surgical Policy for Central Liver Tumors

CompletedOBSERVATIONAL
Enrollment

15

Participants

Timeline

Start Date

January 31, 2004

Primary Completion Date

January 31, 2007

Study Completion Date

May 31, 2007

Conditions
Colorectal Liver MetastasesHepatocellular Carcinoma
Interventions
PROCEDURE

Ultrasound-guided hepatectomy

"After laparotomy and staging by intraoperative ultrasound (IOUS), anterior surface of the hepatocaval confluence is exposed. Than, compression by means of the surgeon's finger-tip is applied at the MHV caval confluence verifying at color-Doppler IOUS the disappearance of the blood flow in the MHV or its inversion. Then, MHV clamping itself is carried out, and parenchymal sparing resection would be selected if at least one of these 3 findings is confirmed:~1. Reversal color-Doppler IOUS flow direction in the peripheral portion of the MHV, which suggests the drainage through collateral circulation in the RHV/LHV depending on the side of the MHV branch with reversal flow.~2. Detectable shunting collaterals at color-Doppler IOUS with RHV or LHV.~3. Hepatopetal flow in P5-8 and/or P4inf portal branches. If none of these finding is confirmed and in particular hepatofugal flow direction in the P5-8 and/or P4 inf is detected the hepatectomy has to be extended."

Trial Locations (1)

20089

Istituto Clinico Humanitas, IRCCS, Rozzano

All Listed Sponsors
lead

University of Milan

OTHER

NCT00600522 - Alternative Surgical Policy for Central Liver Tumors | Biotech Hunter | Biotech Hunter