A Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 for Treating Corneal Wounds

PHASE2TerminatedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

December 31, 2007

Primary Completion Date

February 28, 2009

Study Completion Date

February 28, 2009

Conditions
Diabetes
Interventions
DRUG

Thymosin Beta 4 (Tβ4)

There are 2 groups: active drug and placebo. The patients in the active arm receive an administration of 0.01% Tβ4 (w/w) eyedrops to the affected eye, 2 drops 4 times daily (breakfast, lunch, dinner, and bedtime) for 14 days. The first of 4 daily doses will be administered following surgery (vitrectomy).

OTHER

Placebo

There are 2 groups: active drug and placebo. The patients in the placebo arm receive an administration of 0.00% Tβ4(w/w) eyedrops to the affected eye, 2 drops four times a day (QID) (breakfast, lunch, dinner, and bedtime) for 14 days. The first of 4 daily doses will be administered following surgery (vitrectomy).

Trial Locations (5)

28803

Western Carolina Retinal Associates, PA, Asheville

30909

Southeast Retina Center, Augusta

32803

Magruder Eye Institue, Orlando

90033

Doheny Eye Institute, Los Angeles

90301

United Medical Research Institute, Inglewood

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

PPD Development, LP

INDUSTRY

lead

ReGenTree, LLC

INDUSTRY