Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

October 31, 2014

Study Completion Date

October 31, 2014

Conditions
CNS CancerMeningiomaIntracranial HemangiopericytomaHemangioblastomaNeurofibromatosis
Interventions
DRUG

Sunitinib

The study drug will be administered on an outpatient basis. The starting dose will be 50 mg daily for 28 days (4 consecutive weeks) followed by 14 days off for patients not on CYP3A4 inducers or inhibitors. A cycle equals 42 days.

Trial Locations (6)

10065

Memorial Sloan-Kettering Cancer Center, New York

11725

Memorial Sloan-Kettering Cancer Center at Commack, Commack

22908

University of Virginia Health Science Center, Charlottesville

02115

Dana Farber Cancer Institute, Boston

Unknown

Memoral Sloan Kettering Cancer Center, Basking Ridge

University of Pittsburgh Medical Center, Pittsburgh

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

University of Virginia

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

Pfizer

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER