PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer

PHASE1TerminatedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

February 29, 2008

Primary Completion Date

January 31, 2009

Study Completion Date

January 31, 2009

Conditions
Kidney Cancer
Interventions
BIOLOGICAL

PEG-interferon alfa-2b

administered SC on day 1 of each week of therapy. This will most likely be a Monday or a Tuesday. Sorafenib will be initiated on day 15 (start of week 3) of the first course and continued daily without breaks.

DRUG

Sorafenib

GENETIC

gene expression analysis

GENETIC

polymerase chain reaction

GENETIC

reverse transcriptase-polymerase chain reaction

OTHER

flow cytometry

OTHER

immunoenzyme technique

OTHER

laboratory biomarker analysis

Trial Locations (1)

43210

Ohio State University Comprehensive Cancer Center, Columbus

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Schering-Plough

INDUSTRY

lead

Thomas Olencki

OTHER