Estrogen, Diet, Genetics and Endometrial Cancer

Active, not recruitingOBSERVATIONAL
Enrollment

1,315

Participants

Timeline

Start Date

September 25, 2001

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
CancerEndometrial CancerOvarian CancerCorpus UteriEndometrium
Interventions
BEHAVIORAL

Questionnaire

The main questionnaire will cover established risk and protective factors for endometrial and ovarian cancer, as well as other possible risk factors. This includes: menstrual history; pregnancy history; use of hormones for menopausal symptoms or other reasons; smoking history; height and weight; use of oral contraceptives and other methods of birth control; family history of cancer; medical history; demographic characteristics. We will also collect dietary data using the Gladys Block questionnaire, to which we have added a supplement to measure consumption of phytoestrogens. We will also obtain a buccal sample from each respondent as the source of DNA for genetic analysis.

BEHAVIORAL

Questionnaire

"The main questionnaire will cover established risk and protective factors for endometrial and ovarian cancer, as well as other possible risk factors. This includes: menstrual history; pregnancy history; use of hormones for menopausal symptoms or other reasons; smoking history; height and weight; use of oral contraceptives and other methods of birth control; family history of cancer; medical history; demographic characteristics. We will also collect dietary data using the Gladys Block questionnaire, to which we have added a supplement to measure consumption of phytoestrogens. We will also obtain a buccal sample from each respondent as the source of DNA for genetic analysis.~We will conduct interviews mainly by telephone but also in person (at home or another convenient place)if the participant prefers."

Trial Locations (1)

10065

Memorial Sloan-Kettering Cancer Center, New York

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

Rutgers Cancer Institute of New Jersey

OTHER

collaborator

Municipal Institute of Medical Research

UNKNOWN

collaborator

Department of Health and Human Services

FED

collaborator

Penn State University

OTHER

lead

Memorial Sloan Kettering Cancer Center

OTHER