Oral Paricalcitol in Kidney Transplant Recipients

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 31, 2007

Primary Completion Date

November 30, 2011

Study Completion Date

November 30, 2011

Conditions
Transplant; Failure, KidneyRenal Disease, End StageHyperparathyroidism, Secondary
Interventions
DRUG

Paricalcitol

Zemplar® - this medicine, which is the medicine being studied, will be given as a capsule containing 1 microgram of Zemplar® once daily beginning the day after the transplant. It will be continued at the same dose for the first two weeks then, depending on the results of blood and urine testing, will be increased to 2 micrograms daily. The dose will remain at 2 micrograms daily until the end of the study unless there is a medical reason to reduce or stop it or unless the study is stopped early.

OTHER

Corticosteroid Avoidance Immune Suppression Protocol

Induction with Alemtuzumab and maintenance with Tacrolimus and Mycophenolate Mofetil. With standard antimicrobial prophylaxis and calcium supplementation.

Trial Locations (2)

55905

Mayo Clinic, Rochester

85259

Mayo Clinic, Scottsdale

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Abbott

INDUSTRY

lead

Mayo Clinic

OTHER