Evaluation of Octreotide LAR in Prevention of Chemotherapy-induced Diarrhea

PHASE3CompletedINTERVENTIONAL
Enrollment

139

Participants

Timeline

Start Date

April 30, 2008

Primary Completion Date

September 30, 2010

Study Completion Date

September 30, 2010

Conditions
Chemotherapy-induced Diarrhea
Interventions
DRUG

Octreotide Long Acting Release

Patients will receive the first dose of Octreotide LAR (30 mg) at chemotherapy initiation, in addition to a minimum of two more identical monthly doses of Octreotide LAR (with an interval of 28 days between them), until first-line chemotherapy is discontinued or for a maximum of six doses of Octreotide LAR, whichever occurs first.

OTHER

Standard Treatment

Physician treatment of choice for chemotherapy induced diarrhea other than Octreotide LAR.

Trial Locations (11)

Unknown

Biocâncer, Belo Horizonte

CEPON-Centro de Pesquisas Oncologicas, Florianópolis

Hospital Sao Lucas- Faculdade de Medicina da PUCRS, Porto Alegre

Clínica AMO, Salvador

Nucleo de Oncologia da Bahia, Salvador

Faculdade de Medicina do ABC, Santo André

Hosital Alemão Oswaldo Cruz, São Paulo

Hospital A C Camargo/ Fundação Antonio Prudente, São Paulo

Hospital das Clínicas - FMUSP, São Paulo

Instituto Arnaldo Vieira de Carvalho - IAVC, São Paulo

UNIFESP, São Paulo

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY