Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

February 28, 2009

Study Completion Date

June 30, 2010

Conditions
Atrial FibrillationArrhythmia
Interventions
DRUG

Rate Control

Metoprolol 50-100mg

DEVICE

Ablation Therapy

DRUG

Rate Control

Atenolol 50-100mg,

DRUG

Rate control

Propranolol 40-80mg

DRUG

Rate control

Acebutolol 200mg

DRUG

Rate control

Carvedilol 6.25mg

DRUG

Rate Control

Diltiazem 180-240mg

DRUG

Rate Control

Verapamil 180-240mg

DRUG

Rate Control

Digoxin 0.125mg

DRUG

Rhythm Control

Propafenone 450mg

DRUG

Rhythm control

Flecainide 200mg

DRUG

Rhythm control

Sotalol 240mg

DRUG

Rhythm control

Dofetilide 500mcg

DRUG

Rhythm control

Amiodarone 200mg

DRUG

Rhythm control

Quinidine 600-900mg

Trial Locations (10)

19104

University of Pennsylvania Health, Philadelphia

21287

Johns Hopkins Hospital, Baltimore

35233

Universtity of Alabama Hospital, Birminham

43210

Ohio State University Medical Center, Columbus

50314

Mercy Medical Center, Des Moines

55902

Mayo Clinic, Rochester

60626

Loyola University, Maywood

84157

Intermountain Medical Center, Murray

90017

Good Samaritan Hospital, Los Angeles

02115

Brigham and Womens Hospital, Boston

All Listed Sponsors
collaborator

Duke Clinical Research Institute

OTHER

collaborator

Abbott Medical Devices

INDUSTRY

lead

Mayo Clinic

OTHER