NCT00577135View on ClinicalTrials.gov

Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)

PHASE3CompletedINTERVENTIONAL
Enrollment

308

Participants

Timeline

Start Date

February 29, 2008

Primary Completion Date

January 31, 2010

Study Completion Date

February 28, 2010

Conditions
Heart Failure
Interventions
DRUG

Furosemide-Q12 hour bolus

Q12 hours bolus

DRUG

Furosemide-Continuous Infusion

Continuous infusion

DRUG

Furosemide-Low Intensification

1x oral dose

DRUG

Furosemide-High Intensification

2.5x oral dose

Trial Locations (9)

27705

Duke University Medical Center, Durham

30310

Morehouse School of Medicine, Atlanta

55415

Minnesota Heart Failure Network, Minneapolis

55905

Mayo Clinic, Rochester

77030

Baylor College of Medicine, Houston

84107

University of Utah Health Sciences Center, Murray

02115

Brigham and Women's Hospital, Boston

05401

University of Vermont - Fletcher Allen Health Care, Burlington

H1T - 1C8

Montreal Heart Institute, Montreal

Sponsors

Lead Sponsor

Duke University
All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Duke University

OTHER