137
Participants
Start Date
January 31, 2008
Primary Completion Date
November 30, 2010
Study Completion Date
November 30, 2010
OncoGel (Paclitaxel gel)
6.3 mg/mL tumor volume, injected into the esophagus during endoscopy, once, before starting chemoradiotherapy
cisplatin
75 mg/m2 IV (in the vein) once on Day 1 and Day 29
5-FU
1000 mg/m2/day, IV (in the vein) for 4 days (96 hours) for two cycles starting on Day 1 and Day 29
radiation therapy
50.4 Gy, given in 28 treatments, once per day for 5 1/2 weeks
esophageal resection
Removal of esophagus after completion of chemotherapy and radiation therapy
Thomas Jefferson University, Philadelphia
Indiana University Medical Center, Indianapolis
Rush University Medical Center, Chicago
University of Chicago Medical Center, Chicago
University Hospital Brno, Brno
University of Kansas Medical Center, Kansas City
Baylor University Medical Center, Dallas
Digestive Health Specialists of Tyler, Texas, Tyler
University of California San Diego, San Diego
Bombay Hospital & Medical Research Centre, Mumbai
Deenanath Mangeshkar Hospital, Erandwane
Kidwai Memorial Institute of Oncology, Bangalore
Meenakshi Mission Hospital and Research Centre, Madurai
Amrita Institute of Medical Sciences, Kochi
Hospital Jablonec nad Nisou, Jablonec nad Nisou
University Hospital Olomouc, Olomouc
University Hospital Motol, Prague
Massaryk's Hospital in Usti nad Labem, Ústí nad Labem
Samodzielny Publiczny Szpital Kliniczny, Lublin
Samodzielnego Publicznego Szpitala Klinicznego, Szczecin
Lead Sponsor
Boston Scientific Corporation
INDUSTRY