Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults

NACompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

June 30, 2003

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
Obesity
Interventions
BEHAVIORAL

Diet

Participants attended 20 group behavioral modification sessions led by a behaviorist, a registered dietician, and a physical therapist. The meal plans ranged from 1200 to 1500 kilocalories per day, depending on subject sex and BMI, and were designed to achieve ≤1% body weight loss/week. Participants completed daily food records, and were taught a variety of weight management skills. The exercise component included strength, flexibility, balance, and endurance instruction, gradually increasing to 30 minutes of exercise 5 days/week.

PROCEDURE

Gastric bypass surgery

The same surgeon performed all bypass procedures using standard techniques. A small (\~20 ml) proximal gastric pouch was created by stapling the stomach, and a 75-cm Roux-en-Y limb was constructed by transecting the jejunum distal to the ligament of Treitz, and creating a jejunojejunostomy 75 cm distal to the transection.

Trial Locations (1)

63110

Washington University Medical School, St Louis

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Washington University School of Medicine

OTHER

NCT00572624 - Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults | Biotech Hunter | Biotech Hunter