Rituxan and BEAM With Autologous Peripheral Blood Progenitor Transplant for Indolent Lymphoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

May 12, 1998

Primary Completion Date

January 1, 2001

Study Completion Date

September 18, 2009

Conditions
Lymphoma
Interventions
DRUG

Rituxan

375mg/m2 IV on days -20 to -8. Infusion to begin at rate of 50mg/hour for 1st hour.If no toxicity rate may be increased. A second infusion 375mg/m2 given 30days post transplant and again at 60 days post transplant

DRUG

BEAM

BCNU(carmustine)on day -6 300mg/M2 IV, etoposide 100mg/M2 BID on days -5 through -2, cytarabine 100mg/m2 BID on days -5 through -2, melphalan 140mg/m2 IV on day -1

PROCEDURE

Autologous stem cell transplant

following chemotherapy, on day 0 of treatment, the previously stored hematopoietic stem cells will be reinfused via the central venous line

Trial Locations (1)

68198

University of Nebraska Medical Center, Section of Oncology/Hematology, Omaha

All Listed Sponsors
lead

University of Nebraska

OTHER

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