Nutritional Prevention Pilot Trial for Type 1 Diabetes

PHASE2CompletedINTERVENTIONAL
Enrollment

230

Participants

Timeline

Start Date

February 28, 1995

Primary Completion Date

March 31, 2004

Study Completion Date

January 31, 2008

Conditions
Type 1 Diabetes Mellitus
Interventions
DIETARY_SUPPLEMENT

A highly hydrolyzed formula

Weaning to a highly hydrolyzed formula, avoidance of all supplemental food containing cow's milk proteins and/or bovine serum albumin up to the age of 6-8 months

DIETARY_SUPPLEMENT

A regular cow's milk based formula

Weaning to a regular cow's milk based formula supplemented with 20% of the highly hydrolyzed formula used in arm 1 to make the study formulas similar in smell and taste, avoidance of all supplemental food containing cow's milk proteins and/or bovine serum albumin

Trial Locations (18)

13530

Kanta-Häme Central Hospital, Department of Pediatrics, Hämeenlinna

15850

Päijät-Häme Central Hospital, Lahti

20520

University of Turku, Department of Virology, Turku

28500

Satakunta Central Hospital, Pori

33520

Tampere University Hospital, Department of Pediatrics, Tampere

40620

Central Finland Central Hospital, Jyväskylä

48210

Kymenlaakso Central Hospital, Department of Pediatrics, Kotka

53130

South Karelia Central Hospital, Lappeenranta

60220

South Ostrobothnia Central Hospital, Seinäjoki

65130

Vaasa Central Hospital, Vaasa

70210

University of Kuopio, Department of Pediatrics, Kuopio

80210

North Karelia Central Hospital, Joensuu

90014

University of Oulu, Department of Pediatrics, Oulu

02740

Jorvi Hospital, Espoo

00290

University of Helsinki, Department of Obstetrics and Gynecology, Helsinki

00300

National Public Health Institute, Helsinki

00610

Helsinki University Hospital, Maternity Hospital, Helsinki

FIN-00290

University of Helsinki, Hospital for Children and Adolescents, Helsinki

All Listed Sponsors
collaborator

Academy of Finland

OTHER

collaborator

European Union

OTHER

collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

Diabetes Research Foundation, Finland

OTHER

collaborator

Novo Nordisk A/S

INDUSTRY

lead

University of Helsinki

OTHER