Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia

PHASE3CompletedINTERVENTIONAL
Enrollment

414

Participants

Timeline

Start Date

June 30, 2001

Primary Completion Date

September 30, 2009

Study Completion Date

December 31, 2014

Conditions
Waldenström MacroglobulinemiaLymphoplasmacytic LymphomaSplenic Marginal Zone Lymphoma
Interventions
DRUG

Chlorambucil

Chlorambucil 8 mg/m² (6 mg/m² if patient aged more than 75 years old) 10 days every 28 days during 12 months By oral route

DRUG

Fludarabine

Fludarabine 40 mg/m² (30 mg/m² if patient aged more than 75 years old) 5 days every 28 days during 6 cycles By oral route

Trial Locations (1)

75013

Hôpital La Pitié-Salpêtrière. 47-83 Bd de l'hôpital, Paris

All Listed Sponsors
collaborator

Lymphoma Study Association

OTHER

collaborator

French Innovative Leukemia Organisation

OTHER

collaborator

Département de Biostatistiques et Informatique Médicale DBIM

UNKNOWN

lead

French Study Group on Chronic Lymphoid Leukemia

NETWORK

NCT00566332 - Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia | Biotech Hunter | Biotech Hunter