Effect of Panitumumab on the Pharmacokinetics of Irinotecan

PHASE1CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

March 31, 2008

Primary Completion Date

March 31, 2009

Study Completion Date

June 30, 2010

Conditions
Metastatic Colorectal Cancer
Interventions
DRUG

Panitumumab

The first infusion of panitumumab will occur on Cycle 1 Day 4. On Cycle 2 Day 1, panitumumab will be administered on the same day as irinotecan and every 2 weeks thereafter.

DRUG

Irinotecan

The first infusion of irinotecan will occur on Cycle 1 Day 1. Irinotecan will be administered on the same day as panitumumab on Cycle 2 Day 1 and every 2 weeks thereafter.

Trial Locations (12)

19104

Research Site, Philadelphia

27599

Research Site, Chapel Hill

37203

Research Site, Nashville

59107

Research Site, Billings

Unknown

Research Site, Billings

Research Site, Chapel Hill

Research Site, Philadelphia

Research Site, Nashville

Research Site, Vancouver

Research Site, Toronto

V5Z 4E6

Research Site, Vancouver

M5G 2M9

Research Site, Toronto

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY

NCT00563316 - Effect of Panitumumab on the Pharmacokinetics of Irinotecan | Biotech Hunter | Biotech Hunter