Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia

NACompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

June 30, 2005

Primary Completion Date

April 30, 2006

Study Completion Date

April 30, 2008

Conditions
Schizophrenia
Interventions
DRUG

Pregnenolone

Pregnenolone 50 mg twice a day (BID) x 2 weeks, Pregnenolone 150 mg BID x 2 weeks, Pregnenolone 250 mg BID x 4 weeks

DRUG

Placebo

Placebo (similar to active comparator) 50 mg BID x 2 weeks, Placebo (similar to active comparator) 150 mg BID x 2 weeks, Placebo (similar to active comparator) 250 mg BID x 4 weeks

Trial Locations (1)

27705

Durham VAMC, Durham

Sponsors
All Listed Sponsors
lead

Durham VA Medical Center

FED