Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 31, 1998

Primary Completion Date

July 31, 2011

Study Completion Date

July 31, 2011

Conditions
Lymphoma
Interventions
DRUG

carmustine

Unique to the Carmustine in Conditioning arm

DRUG

cyclophosphamide

Used in Both Arms

DRUG

etoposide

Used in Both Arms

PROCEDURE

autologous hematopoietic stem cell transplantation

Both arms are given autologous stem cell transplantation

PROCEDURE

peripheral blood stem cell transplantation

Both arms are given peripheral blood stem cell transplantation (Peripheral blood stem cells are the material, autologous transplant is the modality).

RADIATION

total-body irradiation

Unique to the Radiation in Conditioning Arm

DRUG

G-CSF

G-CSF is given in both treatment arms, both to mobilize stem cells before apheresis, and to promote recovery of granulocytes after stem-cell re-infusion.

Trial Locations (2)

85006

Good Samaritan Regional Medical Center, Phoenix

91010-3000

City of Hope National Medical Center--Main Campus, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER

NCT00559104 - Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | Biotech Hunter | Biotech Hunter