NCT00555412 - Staccato Loxapine Multidose PK | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

December 31, 2007

Study Completion Date

December 31, 2007

Conditions

Volunteers on Chronic, Stable Antipsychotic Regimens

Interventions

DRUG

A - 10 mg loxapine q 4 h x 3 (30 mg total)

loxapine aerosol inhalation high dose regimen (30 mg total)

DRUG

B - 10 mg x 1, 5 mg x 2 loxapine q 4 h (20 mg total)

loxapine aerosol inhalation middle dose regimen (20 mg total)

DRUG

C - 5 mg loxapine q 4 h x 3 (15 mg total)

loxapine aerosol inhalation low dose regimen (15 mg total)

DRUG

D - inhaled placebo q 4 h x 3

placebo aerosol inhalation (0 mg total)

Trial Locations (1)

Atlanta Center for Medical Research, Atlanta