NCT00554359 - A Dose Escalation and Safety Study of I5NP in Patients Undergoing Major Cardiovascular Surgery | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

October 31, 2010

Study Completion Date

November 30, 2010

Conditions

Injury of KidneyAcute Renal Failure

Interventions

DRUG

I5NP (a small interfering RNA)

Single IV injection of experimental drug

DRUG

placebo

Single IV injection of saline

Trial Locations (11)

University of Pittsburgh Medical Center, Pittsburgh

George Washington University, Washington D.C.

Cleveland Clinic Foundation, Cleveland

Rabin Medical Center, Petah Tikva

Tel Aviv Sourasky Medical Center, Tel Aviv

Texas Heart Institute at St. Luke's Episcopal Hospital, Houston

Shaare Zedek Medical Center, Jerusalem

Brigham and Women's Hospital, Boston

University of Virginia School of Medicine, Charlottesville

University Hospital of Geneva, Geneva

Lausanne University Hospital (CHUV), Lausanne