Phase II Dasatinib Study in Advanced Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
Advanced Breast Cancer
Interventions
DRUG

Dasatinib

An initial dose of 50 mg PO BID; following 4 weeks of treatment, dose adjustment will be based on inhibition of phosphorylation of FAK and paxillin per biopsy assessment, as well as toxicity assessment.

Trial Locations (3)

27710

Duke University Medical Center, Durham

28204

Presbyterian Health Care, Charlotte

33401

Palm Beach Cancer Center Institute, West Palm Beach

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Duke University

OTHER