Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

260

Participants

Timeline

Start Date

October 16, 2001

Primary Completion Date

March 13, 2007

Study Completion Date

April 2, 2026

Conditions
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemiaLymphomaMultiple Myeloma and Plasma Cell NeoplasmMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative DiseasesPrecancerous/Nonmalignant Condition
Interventions
DRUG

busulfan

DRUG

cyclophosphamide

DRUG

cyclosporine

DRUG

etoposide

DRUG

fludarabine phosphate

DRUG

melphalan

DRUG

methotrexate

DRUG

mycophenolate mofetil

DRUG

sirolimus

DRUG

tacrolimus

PROCEDURE

allogeneic hematopoietic stem cell transplantation

PROCEDURE

peripheral blood stem cell transplantation

RADIATION

total-body irradiation

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER