Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
AMLAcute Myeloid LeukemiaMyelodysplastic Disorders
Interventions
DRUG

Idarubicin

12 mg/m\^2 IV over 1 hour daily (days 1-3)

DRUG

Sorafenib

Starting dose 400 mg by mouth for 7 days

DRUG

Ara-C

1.5 g/m\^2 IV over 24 hours daily (days 1-4)

Trial Locations (1)

77030

The University of Texas M.D. Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER