47
Participants
Start Date
February 20, 1997
Primary Completion Date
May 20, 2010
Study Completion Date
May 20, 2010
indocyanine green
0.5 mg/kg will be administered by IV push to determine clearance
lidocaine
1 mg/kg will be administered to determine metabolic capacity
vinorelbine ditartrate
Varying doses ranging from 30 mg/m2 to 7.5 mg/m2 will be administered based upon liver function
high performance liquid chromatography
Used to determine plasma concentrations of vinorelbine
intracellular fluorescence polarization analysis
Used to determine concentration of lidocaine metabolic capacity
liquid chromatography
Used to determine concentrations of vinorelbine and its metabolites
mass spectrometry
Used to determine concentrations of vinorelbine and its metabolites
pharmacological study
Determination of concentrations of vinorelbine and its metabolites
City of Hope Medical Group, Pasadena
City of Hope Medical Center, Duarte
National Cancer Institute (NCI)
NIH
City of Hope Medical Center
OTHER