Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache

PHASE2CompletedINTERVENTIONAL

Enrollment

542

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

November 30, 2008

Study Completion Date

March 31, 2009

Conditions

Migraine Without AuraMigraine With Aura

Interventions

DRUG

Tonabersat

Tablets, 4 week dose titration and 16 weeks treatment at target dose of 40 mg per day

DRUG

Tonabersat

Tablets: 4 week titration and 16 weeks at target dose of 80 mg per day

DRUG

Placebo

Tablets; 4 week dose titration with 16 weeks at target dose