ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma

PHASE1TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions
Neuroblastoma
Interventions
DRUG

ZD6474

Part A = Starting dose 50 mg/m\^2 by mouth daily for 28 days; Part B, C = Starting dose 50 mg/m\^2 by mouth daily on days 2-28.

DRUG

Retinoic Acid

Part B, C = 80 mg/m\^2 by mouth twice daily for 2 consecutive weeks out of every four weeks (28 days).

Trial Locations (1)

77030

U.T.M.D. Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER