Adding Adefovir Dipivoxil Versus Switching to Entecavir in Patients With Lamivudine-resistant Chronic Hepatitis B

PHASE4CompletedINTERVENTIONAL

Enrollment

219

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

April 30, 2011

Study Completion Date

October 31, 2012

Conditions

Chronic Hepatitis B

Interventions

DRUG

combination of lamivudine+adefovir vs entecavir

Lamivudine 100 mg/day, Adefovir 10 mg/day, Entecavir 0.5 mg/day

Trial Locations (2)

Korea University Ansan Hospital, Ansan

Korea University Anam Hospital, Seoul