Study of SGN-40, Lenalidomide, and Dexamethasone in Patients With Multiple Myeloma

PHASE1CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

January 31, 2010

Study Completion Date

February 28, 2010

Conditions
Multiple Myeloma
Interventions
DRUG

SGN-40

2-12 mg/kg IV (in the vein) on Days 1, 4, 8, 15, and 22 of Cycle 1; 4-12 mg/kg IV (in the vein) on Days 1, 8, 15, and 22 of Cycles 2-4; 4-12 mg/kg IV (in the vein) on Days 1, 8, and 15 of Cycles 5-8.

DRUG

lenalidomide

Up to 25 mg daily of a 21-day cycle.

DRUG

dexamethasone

40 mg administered weekly.

Trial Locations (9)

10021

Weill Medical College of Cornell University, New York

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

48201

Barbara Ann Karmanos Cancer Institute, Detroit

57105

Avera Cancer Institute, Sioux Falls

68114

Nebraska Methodist Hospital, Omaha

75246

Baylor University Medical Center, Dallas

80218

Rocky Mountain Cancer Center, Denver

02115

Dana Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Seagen Inc.

INDUSTRY

NCT00525447 - Study of SGN-40, Lenalidomide, and Dexamethasone in Patients With Multiple Myeloma | Biotech Hunter | Biotech Hunter