A Phase II Study of a Continuous Hepatic Arterial Infusion Combination Therapy With OPC-18 and 5-FU in Patients With Highly Advanced Hepatocellular Carcinoma

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

January 31, 2010

Study Completion Date

January 31, 2010

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

OPC-18

OPC-18: 500IU \* 3 times a week, sc 5-FU : 500mg infusion for 5days into hepatic artery

DRUG

cisplatin

infusion into hepatic artery with cisplatin 10mg and 5-FU 250mg a day

Trial Locations (7)

Chubu Region

Chugoku Region

Hokkaido Region

Kanto Region

Kinki Region

Kyushu Region

Tohoku Region