2
Participants
Start Date
December 31, 2007
Primary Completion Date
February 29, 2008
Study Completion Date
April 30, 2008
CHR-2797 (tosedostat)
Once daily, oral ingestion of CHR-2797 capsules(PhaseI: 120mg, 160mg or 200mg depending on cohort or Phase II: recommended dose) capsules until progressive disease or withdrawal from the study
erlotinib
Once daily, oral ingestion of erlotinib tablets 150mg tablets until progressive disease or withdrawal from the study. Per protocol, the Investigator may reduce the dose of erlotinib or cease treatment with erlotinib(per label) with Sponsor approval.
Richmond University Medical Center, Staten Island
Montefiore Medical Center, The Bronx
Carolina BioOncology Institute, Huntersville
Clinworks Research Center, Charlotte
Oncology Associates of West Kentucky, Paducah
Tower Cancer Research Foundation, Beverly Hills
Medical Oncology Care Associates, Orange
Lead Sponsor
Chroma Therapeutics
INDUSTRY