60
Participants
Start Date
August 31, 2007
Primary Completion Date
April 30, 2008
Study Completion Date
June 30, 2008
ISIS 325568
"4 arms of single dose s.c. injections: A 50 mg B 100 mg C 200 mg D 400 mg 4 arms of multi-dose: 3 i.v. infusions over 1 week followed by 5 weekly s.c. injections AA 50 mg BB 100 mg CC 200 mg DD 400 mg or EE 50 mg~Placebo: 0.9% Sodium Chloride"
Centre for Human Drug Research, Leiden
Lead Sponsor
Ionis Pharmaceuticals, Inc.
INDUSTRY