Study of ABT-869 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)

PHASE2CompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

June 30, 2011

Study Completion Date

June 30, 2012

Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG

ABT-869 .25 mg/kg

Subjects will take linifanib (ABT-869) based on body weight. Dosing will be determined at baseline and will be based on randomization to either 0.10 mg or 0.25 mg of ABT-869 per kilogram of body weight.

DRUG

ABT-869 0.10 mg/kg

Subjects will take linifanib (ABT-869) based on body weight. Dosing will be determined at baseline and will be based on randomization to either 0.10 mg or 0.25 mg of ABT-869 per kilogram of body weight.

Trial Locations (28)

10002

Site Reference ID/Investigator# 5640, Taipei

13274

Site Reference ID/Investigator# 7756, Marseille

14263

Site Reference ID/Investigator# 5652, Buffalo

19718

Site Reference ID/Investigator# 7868, Newark

27403

Site Reference ID/Investigator# 6777, Greensboro

28211

Site Reference ID/Investigator# 6184, Charlotte

31059

Site Reference ID/Investigator# 8068, Toulouse

34952

Site Reference ID/Investigator# 7616, Port Saint Lucie

38120

Site Reference ID/Investigator# 5650, Memphis

40705

Site Reference ID/Investigator# 5663, Taichung

46202

Site Reference ID/Investigator# 5269, Indianapolis

60201

Site Reference ID/Investigator# 6739, Evanston

60426

Site Reference ID/Investigator# 8100, Harvey

60637

Site Reference ID/Investigator# 5648, Chicago

63110

Site Reference ID/Investigator# 6042, St Louis

90033

Site Reference ID/Investigator# 5617, Los Angeles

92708

Site Reference ID/Investigator# 7194, Fountain Valley

94805

Site Reference ID/Investigator# 8069, Villejuif

95817

Site Reference ID/Investigator# 7934, Sacramento

119228

Site Reference ID/Investigator# 5660, Singapore

169610

Site Reference ID/Investigator# 5534, Singapore

80045-0510

Site Reference ID/Investigator# 5646, Aurora

06708

Site Reference ID/Investigator# 6627, Waterbury

07018

Site Reference ID/Investigator# 6680, East Orange

08043

Site Reference ID/Investigator# 5603, Voorhees Township

L4M 6M2

Site Reference ID/Investigator# 6040, Barrie

K1H 8L6

Site Reference ID/Investigator# 5275, Ottawa

M5G 2M9

Site Reference ID/Investigator# 6572, Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

AbbVie (prior sponsor, Abbott)

INDUSTRY