Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

June 30, 2003

Primary Completion Date

February 28, 2010

Study Completion Date

February 28, 2010

Conditions
Prostate Cancer
Interventions
DRUG

Docetaxel

30 mg/m\^2 by vein (IV) Weekly Over 60 Minutes on Days 1, 8, 15, and 22. This will be followed by 2 weeks with no docetaxel.

DRUG

Imatinib Mesylate

600 mg by mouth (PO) Daily x 42 Days.

DRUG

Leuprolide

Hormone injections given every other month or every 3 months, as determined by the doctor.

DRUG

Goserelin Acetate

Hormone injections given every other month or every 3 months, as determined by the doctor.

Trial Locations (1)

77030

U.T.M.D. Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis Pharmaceuticals

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER