282
Participants
Start Date
July 31, 2007
Primary Completion Date
June 30, 2010
Study Completion Date
June 30, 2010
Eraxis (anidulafungin)
Subjects will receive IV anidulafungin (200 mg loading dose followed by 100 mg maintenance doses QD) for 5-28 days. This will be followed by oral therapy with fluconazole at 400 mg once daily or voriconazole at 200 mg twice daily until 14 days after the last positive culture. Fluconazole will be used if the baseline cultures are positive for C. albicans or C. parapsilosis while voriconazole will be used if cultures are positive for C. glabrata or other non-albicans species.
Diflucan (fluconazole)
Subjects will receive IV anidulafungin (200 mg loading dose followed by 100 mg maintenance doses QD) for 5-28 days. This will be followed by oral therapy with fluconazole at 400 mg once daily or voriconazole at 200 mg twice daily until 14 days after the last positive culture. Fluconazole will be used if the baseline cultures are positive for C. albicans or C. parapsilosis.
Vfend (voriconazole)
Subjects will receive IV anidulafungin (200 mg loading dose followed by 100 mg maintenance doses QD) for 5-28 days. This will be followed by oral therapy with fluconazole at 400 mg once daily or voriconazole at 200 mg twice daily until 14 days after the last positive culture. Fluconazole will be used if the baseline cultures are positive for C. albicans or C. parapsilosis while voriconazole will be used if cultures are positive for C. glabrata or other non-albicans species.
Pfizer Investigational Site, Albany
Pfizer Investigational Site, Buffalo
Pfizer Investigational Site, Rochester
Pfizer Investigational Site, Pittsburgh
Pfizer Investigational Site, Philadelphia
Pfizer Investigational Site, West Reading
Pfizer Investigational Site, Newark
Pfizer Investigational Site, Newark
Pfizer Investigational Site, Wilmington
Pfizer Investigational Site, Washington D.C.
Pfizer Investigational Site, Baltimore
Pfizer Investigational Site, Baltimore
Pfizer Investigational Site, Greenville
Pfizer Investigational Site, Charleston
Pfizer Investigational Site, Atlanta
Pfizer Investigational Site, Jacksonville
Pfizer Investigational Site, Orlando
Pfizer Investigational Site, Orlando
Pfizer Investigational Site, Orlando
Pfizer Investigational Site, Miami
Pfizer Investigational Site, Birmingham
Pfizer Investigational Site, Birmingham
Pfizer Investigational Site, Royal Oak
Pfizer Investigational Site, Detroit
Pfizer Investigational Site, Detroit
Pfizer Investigational Site, Minneota
Pfizer Investigational Site, Butte
Pfizer Investigational Site, Springfield
Pfizer Investigational Site, Springfield
Pfizer Investigational Site, Springfield
Pfizer Investigational Site, Little Rock
Pfizer Investigational Site, Houston
Pfizer Investigational Site, Los Angeles
Pfizer Investigational Site, San Francisco
Pfizer Investigational Site, San Francisco
Pfizer Investigational Site, Portland
Pfizer Investigational Site, Springfield
Pfizer Investigational Site, Camden
Pfizer Investigational Site, Greenville
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Seoul
Lead Sponsor
Pfizer
INDUSTRY