50
Participants
Start Date
February 29, 2004
Primary Completion Date
August 31, 2014
Study Completion Date
August 31, 2014
Docetaxel
25 mg/m2 IV over 30 minutes for 4 weeks, followed by 2 weeks off therapy.
ZD1839
250 mg by mouth daily, without break.
Dexamethasone
"Course #1: 3 doses of prophylactic Dexamethasone 4mg orally every 12 hours, starting the night before the Docetaxel infusion.~Course #2: If no hypersensitivity reactions and no significant fluid retention during course 1, the Dexamethasone is reduced to 4mg orally twice daily on the day of therapy.~Course #3 and subsequent courses: If no hypersensitivity reactions and no significant fluid retention during course 2, the Dexamethasone is reduced to 4mg orally one hour before treatment."
University of Texas MD Anderson Cancer Center, Houston
Collaborators (1)
AstraZeneca
INDUSTRY
M.D. Anderson Cancer Center
OTHER