2
Participants
Start Date
September 30, 2007
Primary Completion Date
April 30, 2009
Study Completion Date
April 30, 2009
Iodine I -01 Tositumomab (Bexxar)
"Patients will be treated in two dosing phases, each phase includes two infusions. The first phase, termed dosimetric dose, involves an intravenous administration of 450 mg unlabeled tositumomab followed by an intravenous administration of 5 mCi (0.18 GBq) of I-131 tositumomab for the purpose of determining the rate of whole body clearance of radioactivity (residence time) so that the administered activity (mCi or GBq) to deliver a 75 cGy (or 65 cGy for patients with baseline platelet count from 100,000 to 149,999/mm\^3) total body radiation dose can be calculated."
External Beam Radiation Therapy
All patients are to receive 20 Gy in 10 fractions of 200 cGy to the PTV
University of Florida, Gainesville
Collaborators (1)
GlaxoSmithKline
INDUSTRY
University of Florida
OTHER