Study to Treat Relapsed Follicular Non-Hodgkin's Lymphoma With Radiation and Bexxar

PHASE2TerminatedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

April 30, 2009

Study Completion Date

April 30, 2009

Conditions
Non-Hodgkin's LymphomaFollicular Lymphoma
Interventions
DRUG

Iodine I -01 Tositumomab (Bexxar)

"Patients will be treated in two dosing phases, each phase includes two infusions. The first phase, termed dosimetric dose, involves an intravenous administration of 450 mg unlabeled tositumomab followed by an intravenous administration of 5 mCi (0.18 GBq) of I-131 tositumomab for the purpose of determining the rate of whole body clearance of radioactivity (residence time) so that the administered activity (mCi or GBq) to deliver a 75 cGy (or 65 cGy for patients with baseline platelet count from 100,000 to 149,999/mm\^3) total body radiation dose can be calculated."

PROCEDURE

External Beam Radiation Therapy

All patients are to receive 20 Gy in 10 fractions of 200 cGy to the PTV

Trial Locations (1)

32610

University of Florida, Gainesville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

University of Florida

OTHER