NCT00473486 - Study in Patients With Advanced Non-Small Cell Lung Cancer Treated With Pemetrexed and Carboplatin Plus or Minus Sorafenib | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

August 31, 2008

Study Completion Date

January 31, 2010

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

pemetrexed, carboplatin, sorafenib

"Ph. 1: pemetrexed 500mg/m² iv day 1; carboplatin AUC 6 iv day 1; Sorafenib 200mg po bid days 2-19; 400mg po bid days 2-19~Ph 2: pemetrexed 500mg/m² iv day 1; carboplatin AUC 6 iv day 1;sorafenib depending on results of Ph 1"

DRUG

pemetrexed, carboplatin, placebo

Ph 2: pemetrexed 500mg/m² iv day 1; carboplatin AUC 6 iv day 1; placebo day 2-19

Trial Locations (1)

48145

University of Muenster, Dept. of Medicine, Hematology / Oncology, Münster