110
Participants
Start Date
July 31, 2006
Primary Completion Date
August 31, 2012
Study Completion Date
November 30, 2012
Cetuximab
250mg/m2(day 1, weekly x 10);
5-FU
600 mg/m2/day; days 0-5 (120 h total) every other week x 5
Hydroxyurea
500 mg PO BID, days 0-5 every other week x 5
Twice-daily radiation
150 cGy per fraction, days 1-5, every other week x 5 (total duration 10 weeks)
Cisplatin
100 mg/m2, week 1 and 4 on day 1 (or 2)
Accelerated fraction radiotherapy with concomitant boost
72 Gy/42 F/6 W (3-D or IMRT based). Total duration 7 weeks.
University of Chicago, Chicago
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
University of Chicago
OTHER