NCT00468104View on ClinicalTrials.gov

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 30, 2004

Primary Completion Date

October 31, 2008

Study Completion Date

August 31, 2009

Conditions
Pleural Effusion Associated With Pulmonary InfectionBacterial Pleural Effusion Other Than Tuberculosis
Interventions
DRUG

Alteplase

25 Mg of Alteplase in 100 cc of normal saline was instilled intrapeurally for daily for three days

DRUG

Placebo

Placebo in 100 cc of normal saline was instilled intrapleurally daily for three days

Trial Locations (1)

68114

Nebraska Methodist Hospital, Omaha

Sponsors

Collaborators (1)

Genentech, Inc.
All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Midwest Pulmonary and Critical Care

OTHER