Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment

PHASE4CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

March 31, 2010

Study Completion Date

April 30, 2010

Conditions
Obsessive Compulsive Disorder
Interventions
DRUG

Clomipramine (fluoxetine plus clomipramine)

Clomipramine at maximum dosage of 75mg per day plus fluoxetine at maximum dosage of 40mg per day

DRUG

Quetiapine (fluoxetine plus quetiapine)

Quetiapine at maximum tolerated dosage of 200mg per day plus fluoxetine at maximum dosage of 40mg per day

DRUG

Placebo (fluoxetine plus placebo)

Placebo plus fluoxetine at maximum dosage of 80mg per day

Trial Locations (1)

05403-010

Institute of Psychiatry, São Paulo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

collaborator

Novartis

INDUSTRY

lead

University of Sao Paulo

OTHER