Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial

NACompletedINTERVENTIONAL
Enrollment

980

Participants

Timeline

Start Date

August 31, 2003

Primary Completion Date

May 31, 2012

Study Completion Date

May 31, 2016

Conditions
Cryptogenic Stroke
Interventions
DEVICE

AMPLATZER PFO Occluder

patent foramen ovale closure device

OTHER

Standard of Care - Medical Management

Medical management - aspirin alone, Coumadin alone, Clopidogrel alone, aspirin combined with dipyridamole

Trial Locations (69)

12208

Albany Medical Center, Albany

14226

DENT Neurologic Institute, Amherst

14642

University of Rochester, Rochester

17033

Penn State Milton South Hershey Medical Center, Hershey

17543

Lancaster General Hospital, Lancaster

18105

LeHigh Valley Hospital, Allentown

19067

St. Mary's Medical Center, Langhorne

20010

Washington Hospital Center, Washington D.C.

20037

George Washington University Hospital, Washington D.C.

21014

Midatlantic Cardiovascular Associates, Towson

23454

Sentara Virginia Beach General Hospital, Virginia Beach

25304

Charleston Area Medical Center, Charleston

27410

Moses H. Cone Memorial Hospital, Greensboro

27710

Duke University Medical Center, Durham

29425

Medical University of South Carolina, Charleston

32204

St. Vincent's Medical Center, Jacksonville

35249

University of Alabama, Birmingham

37205

St. Thomas Neurology, Nashville

40536

University of Kentucky, Lexington

43210

Ohio State University, Columbus

44106

University Hospitals of Cleveland, Cleveland

44320

Neurology and Neuroscience Associates, Akron

46237

Indiana Heart Physicians, Indianapolis

50314

Ruan Neurology, Des Moines

52242

University of Iowa Hospitals and Clinics, Iowa City

53226

Medical College of Wisconsin, Milwaukee

53792

University of Wisconsin Hospital, Madison

54449

Marshfield Clinic, Marshfield

55407

Abbott Northwestern Hospital, Minneapolis

55426

Methodist Hospital/Park Nicollet Medical Center, Saint Louis Park

55455

University of Minnesota, Minneapolis

55805

St. Mary's Duluth Clinic, Duluth

57108

North Central Heart Institute, Sioux Falls

60463

Neurologic Associates Inc, Palos Heights

61637

OSF St. Francis Medical Center, Peoria

62702

Southern Illinois University Neurology, Springfield

63110

Washington University, St Louis

66160

Kansas University Medical Center, Kansas City

70121

Ochsner Clinic Foundation, New Orleans

77030

University of Texas Houston Health Science Center, Houston

80120

South Denver Cardiology Associates, Littleton

80262

University of Colorado, Denver

80538

Medical Center of the Rockies, Loveland

85259

Mayo Clinic, Scottsdale

90033

LAC + USC Medical Center, Los Angeles

90095

UCLA, Los Angeles

92123

Sharp Memorial Hospital, San Diego

94115

Kaiser Permanente, San Francisco

94609

Summit Medical Center, Oakland

97225

Providence St. Vincent's Medical Center, Portland

97329

Oregon Stroke Center, OHSU, Portland

98104

UW Medicine Stroke Center, Seattle

60611-3078

Northwestern University, Chicago

60637-1470

University of Chicago, Chicago

02111

Tufts Medical Center, Boston

48109-0316

University of Michigan Health System, Ann Arbor

68198-2045

University of Nebraska Medical Center, Omaha

08034

Our Lady of Lourdes Medical Center, Cherry Hill

07103

University of Medicine and Dentistry of New Jersy, Newark

37232-8802

Vanderbilt University, Nashville

75390-8897

UT Southwestern Medical School, Dallas

T2N 2T9

University of Calgary, Calgary

T6G 2B7

University of Alberta, Edmonton

V3L 3W5

Royal Columbian Hospital, New Westminster

V5Z 1M9

Vancouver General Hospital, Vancouver

V5Z 1Y6

St. Paul's Hospital, Vancouver

N6G 2V2

Stroke Prevention & Atherosclerosis Research Center (SPARC) - Robarts Research Institute, London

M5G 2C4

Toronto General Hospital, Toronto

H1T 1C8

Montreal Heart Institute, Montreal

Sponsors
All Listed Sponsors
lead

Abbott Medical Devices

INDUSTRY