FCR and Bevacizumab in the Treatment of Relapsed Chronic Lymphocytic Leukemia (CLL)

PHASE2CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

October 31, 2014

Study Completion Date

October 31, 2014

Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG

Fludarabine

25 mg/m\^2 IV over 30 minutes daily for 3 days

DRUG

Cyclophosphamide

250 mg/m\^2 IV over 30 minutes daily for 3 days

DRUG

Rituximab

375 mg/m\^2 IV on Day 1 by prolonged infusion. All subsequent doses 500 mg/m\^2 IV 30-minute infusion.

DRUG

Bevacizumab

10 mg/Kg IV on Day 3, course 1 over 30-90 minutes

Trial Locations (1)

77030

University of Texas MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER