NCT00446004 - Effect of a Proton Pump Inhibitor on Gleevec® in Healthy Volunteers | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

August 31, 2009

Study Completion Date

August 31, 2009

Conditions

Healthy

Interventions

DRUG

Imatinib Mesylate

Dosage form: tablets Dosage: 400 mg Frequency \& duration: On an 18-day schedule, one dose administered once on day 1 and once on day 15 (2 doses total)

DRUG

Omeprazole

Dosage form: capsules Dosage: 40 mg Frequency: On an 18-day schedule, once daily day 10 through day 16 (for Arm A); or once daily day -4 through day 1 (for Arm B)

Trial Locations (1)

15232 / 15213

University of Pittsburgh Cancer Institute / Clinical and Translational Research Center (Hillman Cancer Center and Montefiore University Hospital locations), Pittsburgh