Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

151

Participants

Timeline

Start Date

February 28, 2003

Study Completion Date

May 31, 2007

Conditions
Spine Surgery
Interventions
DRUG

Tranexamic acid

"Eligible patients who have consented to be in the study and have been randomised to be in Arm A will receive 10 mg/kg of tranexamic acid, and then a continuous infusion of 1 mg/kg/hr of tranexamic acid."

DRUG

Placebo

"Eligible patients who have consented to be in the study and have been randomised to be in Arm B will receive 10 mg/kg of placebo followed by a continuous infusion of 1 mg/kg/hr of placebo."

Trial Locations (3)

L5B 1B8

Trillium Health Centre, Mississauga

M5B 1W8

St. Michael's Hospital, Toronto

M5T 2S8

Department of Anesthesia and Orthopedics; Toronto Western Hospital, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER

NCT00444470 - Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery | Biotech Hunter | Biotech Hunter